Carbapenem-resistant enterobacteriacae: a challenge for early detection and infection control

نویسندگان

  • C Fankhauser
  • A Cherkaoui
  • G Renzi
  • M Abbas
  • J Schrenzel
  • D Pittet
  • S Harbarth
چکیده

Results Between October 2009 January 2010, we identified 1 imported case of KPC (origin, Southern Italy) and 3 cases of NDM-1 producing Enterobacteriaceae, transferred from hospitals in India (1), Pakistan (2) and Serbia/ France(3). Patient 1on admission digestive carrier of E. coli blaNDM-1. Patient 2digestive carrier of P. mirabilis blaNDM-1 detected after extended hospitalization and antibiotic therapy Patient 3hospitalized in Serbia and France, with K. pneumonia blaNDM-1 urinary tract infection on admission. All 3 patients were carriers of other multiresistant, Gram-negative bacteria on admission. The NDM-1 molecular identification was made retrospectively in October 2010. Patient 4 was admitted for elective surgery, without prior history of hospitalization. A urine culture yielded K. pneumoniablaKPC-2. The patient was put under strict contact precautions; but developed a surgical site infection with treatment challenges related to dose finding, availability, toxicity of antibiotics. No secondary cases were found due to early screening and preemptive isolation.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2011